reviewTop 1% cited
Inflammasomes: mechanism of assembly, regulation and signalling
Nature reviews. Immunology · 2016 · Vol. 16(7) · pp. 407–420
Petr Brož✉(University of Basel)Vishva M. Dixit✉
Inflammasome and immune disordersKawasaki Disease and Coronary Complicationsinterferon and immune responsesInflammasomeAIM2PyroptosisCell biologyMechanism (biology)SignallingCaspasePattern recognition receptorSignalling pathwaysBiology
MeSH terms
AnimalsHumansSignal TransductionInflammasomes
Citations
3,348
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References
The Inflammasome
Molecular Cell · 2002 · 5,936 citations
Caspase‐11 activates a canonical NLRP3 inflammasome by promoting K <sup>+</sup> efflux
European Journal of Immunology · 2015 · 502 citations
Activation and regulation of the inflammasomes
Nature reviews. Immunology · 2013 · 2,842 citations
K+ Efflux Is the Common Trigger of NLRP3 Inflammasome Activation by Bacterial Toxins and Particulate Matter
Immunity · 2013 · 2,085 citations
The AIM2 inflammasome is essential for host defense against cytosolic bacteria and DNA viruses
Nature Immunology · 2010 · 1,284 citations
IFI16 is an innate immune sensor for intracellular DNA
Nature Immunology · 2010 · 1,616 citations
A small-molecule inhibitor of the NLRP3 inflammasome for the treatment of inflammatory diseases
Nature Medicine · 2015 · 2,700 citations
Apoptosis, Pyroptosis, and Necrosis: Mechanistic Description of Dead and Dying Eukaryotic Cells
Infection and Immunity · 2005 · 2,191 citations
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