article Open AccessTop 1% cited
Activation of the NALP3 inflammasome is triggered by low intracellular potassium concentration
Cell Death and Differentiation · 2007 · Vol. 14(9) · pp. 1583–1589
Virginie Pétrilli✉(University of Lausanne)Stéphanie Papin(University of Lausanne)Catherine Dostert(University of Lausanne)Annick Mayor(University of Lausanne)Fabio Martinon(Harvard University)Jürg Tschopp(University of Lausanne)
Inflammasome and immune disordersCalcium signaling and nucleotide metabolismStreptococcal Infections and TreatmentsInflammasomeNALP3Caspase 1Interleukin 18AIM2Proinflammatory cytokineIntracellularChemistryCell biologyPyroptosis
MeSH terms
NLR Family, Pyrin Domain-Containing 3 ProteinAnimalsCalcium-Binding ProteinsCarrier ProteinsCell LineHumansInflammationMice, Inbred BALB CMice, Inbred C57BLPotassiumMacrophages, PeritonealCaspase 1Interleukin-18Apoptosis Regulatory ProteinsMice
Funding
- National Science Foundation
- Schweizerischer Nationalfonds zur Förderung der Wissenschaftlichen Forschung
Citations
1,418
FWCI
25.20
field-weighted impact
References
38
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100%
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Citations per year
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References
The Inflammasome
Molecular Cell · 2002 · 5,936 citations
Inflammatory caspases and inflammasomes: master switches of inflammation
Cell Death and Differentiation · 2006 · 819 citations
NALP3 Forms an IL-1β-Processing Inflammasome with Increased Activity in Muckle-Wells Autoinflammatory Disorder
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