reviewTop 10% cited
Physical Stability of Proteins in Aqueous Solution: Mechanism and Driving Forces in Nonnative Protein Aggregation
Pharmaceutical Research · 2003 · Vol. 20(9) · pp. 1325–1336
Eva Y.✉Sampathkumar Krishnan(Amgen (United States))Theodore W. Randolph(University of Colorado Boulder)John F. Carpenter(University of Colorado Health)
Protein purification and stabilityEnzyme Structure and FunctionProteins in Food SystemsProtein aggregationChemistrySterilization (economics)PreservativeSalt (chemistry)BiochemistryFood scienceOrganic chemistryBusiness
MeSH terms
Drug StabilityDrug StorageHydrogen-Ion ConcentrationProtein ConformationProteinsSolventsSurface-Active AgentsTemperatureWaterProtein FoldingPharmaceutical Solutions
Funding
- National Science Foundation
- U.S. Department of Education
- Amgen
Citations
1,362
FWCI
8.43
field-weighted impact
References
108
Percentile
99%
vs. same field & year
Citations per year
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References
Stability of Protein Pharmaceuticals
Pharmaceutical Research · 1989 · 1,072 citations
Infrared Spectroscopic Studies of Lyophilization‐ and Temperature‐Induced Protein Aggregation
Journal of Pharmaceutical Sciences · 1995 · 457 citations
Effect of Environmental Factors on the Kinetics of Insulin Fibril Formation: Elucidation of the Molecular Mechanism
Biochemistry · 2001 · 1,188 citations
Dominant forces in protein folding
Biochemistry · 1990 · 3,775 citations
Stabilization of protein structure by sugars
Biochemistry · 1982 · 1,077 citations
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