articleTop 1% cited
Infrared Spectroscopic Studies of Lyophilization‐ and Temperature‐Induced Protein Aggregation
Journal of Pharmaceutical Sciences · 1995 · Vol. 84(4) · pp. 415–424
Aichun Dong(University of Colorado Health)Steven J. Prestrelski(Amgen (United States))Steven Allison(University of Colorado Health)John F. Carpenter✉(University of Colorado Health)
Enzyme Structure and FunctionProtein Structure and DynamicsProtein purification and stabilityProtein aggregationSpectroscopyChemistryInfrared spectroscopyFreeze-dryingProtein structureProtein stabilityBiophysicsChromatographyBiochemistry
MeSH terms
ChymotrypsinFreeze DryingL-Lactate DehydrogenasePhosphofructokinase-1ProteinsSpectrophotometry, InfraredTemperatureThiocyanates
Funding
- American Foundation for Pharmaceutical Education
- Office of Naval Research
Citations
457
FWCI
15.08
field-weighted impact
References
59
Percentile
100%
vs. same field & year
Citations per year
Cited by
Instability, stabilization, and formulation of liquid protein pharmaceuticals
International Journal of Pharmaceutics · 1999 · 1,052 citations
Hydrogen Bonding between Sugar and Protein Is Responsible for Inhibition of Dehydration-Induced Protein Unfolding
Archives of Biochemistry and Biophysics · 1999 · 535 citations
Rational Design of Stable Lyophilized Protein Formulations: Some Practical Advice
Pharmaceutical Research · 1997 · 671 citations
Trehalose: Current Use and Future Applications
Journal of Pharmaceutical Sciences · 2011 · 472 citations
Effects of glycosylation on the stability of protein pharmaceuticals
Journal of Pharmaceutical Sciences · 2008 · 636 citations
Physical Stability of Proteins in Aqueous Solution: Mechanism and Driving Forces in Nonnative Protein Aggregation
Pharmaceutical Research · 2003 · 1,362 citations
Lyophilization and development of solid protein pharmaceuticals
International Journal of Pharmaceutics · 2000 · 1,143 citations
Protein aggregation and its inhibition in biopharmaceutics
International Journal of Pharmaceutics · 2005 · 966 citations
References
Determination of protein secondary structure by Fourier transform infrared spectroscopy: A critical assessment
Biochemistry · 1993 · 1,525 citations
Protein secondary structures in water from second-derivative amide I infrared spectra
Biochemistry · 1990 · 1,315 citations
Citation Network
How this paper connects to the literature. Drag to explore, click any node to open that paper.