articleTop 10% cited
Challenges in the development of high protein concentration formulations
Journal of Pharmaceutical Sciences · 2004 · Vol. 93(6) · pp. 1390–1402
Protein purification and stabilityAdvanced Drug Delivery SystemsDrug Solubulity and Delivery SystemsSolubilityChemistryDilutionProtein stabilityHigh proteinProtein aggregationChromatographySize-exclusion chromatographyBiochemistryOrganic chemistry
MeSH terms
AnimalsChemistry, PharmaceuticalHumansProteinsSolubilityTechnology, Pharmaceutical
Citations
861
FWCI
5.52
field-weighted impact
References
58
Percentile
97%
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Citations per year
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References
Rational Design of Stable Lyophilized Protein Formulations: Some Practical Advice
Pharmaceutical Research · 1997 · 671 citations
Stability of Protein Pharmaceuticals
Pharmaceutical Research · 1989 · 1,072 citations
Physical Stability of Proteins in Aqueous Solution: Mechanism and Driving Forces in Nonnative Protein Aggregation
Pharmaceutical Research · 2003 · 1,362 citations
Stabilization of protein structure by sugars
Biochemistry · 1982 · 1,077 citations
Salt effects on hydrophobic interactions in precipitation and chromatography of proteins: An interpretation of the lyotropic series
Archives of Biochemistry and Biophysics · 1977 · 913 citations
Modern analytical ultracentrifugation in protein science: A tutorial review
Protein Science · 2002 · 769 citations
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