reviewTop 1% cited
Involvement of PI3K/Akt pathway in cell cycle progression, apoptosis, and neoplastic transformation: a target for cancer chemotherapy
Leukemia · 2003 · Vol. 17(3) · pp. 590–603
Fuju Chang✉(East Carolina University)J T Lee(East Carolina University)Patrick M. Navolanic(East Carolina University)Linda S. Steelman(East Carolina University)J G Shelton(East Carolina University)William L. Blalock(University of Florida Health)Richard A. Franklin(East Carolina University)James A. McCubrey(East Carolina University)
PI3K/AKT/mTOR signaling in cancerCancer-related Molecular PathwaysCancer Mechanisms and TherapyPI3K/AKT/mTOR pathwayProtein kinase BSignal transductionCancer researchBiologyCarcinogenesisCell biologyCell cycleKinaseNeoplastic transformation
MeSH terms
Antineoplastic AgentsCell CycleCell Transformation, NeoplasticHumansProto-Oncogene ProteinsApoptosisProtein Serine-Threonine KinasesPhosphatidylinositol 3-KinasesProto-Oncogene Proteins c-akt
Funding
- American Cancer Society
- National Institutes of Health
Citations
1,188
FWCI
14.69
field-weighted impact
References
167
Percentile
100%
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References
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Molecular Endocrinology · 2000 · 422 citations
Specificity and mechanism of action of some commonly used protein kinase inhibitors
Biochemical Journal · 2000 · 4,060 citations
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