reviewTop 1% cited
Phosphoinositide 3-kinases: A conserved family of signal transducers
Trends in Biochemical Sciences · 1997 · Vol. 22(7) · pp. 267–272
Bart Vanhaesebroeck✉(Ludwig Cancer Research)Sally J. Leevers(Ludwig Cancer Research)George Panayotou(Ludwig Cancer Research)Michael D. Waterfield(Ludwig Cancer Research)
PI3K/AKT/mTOR signaling in cancerProtein Kinase Regulation and GTPase SignalingCellular transport and secretionCell biologyKinaseSignallingSignal transductionFunction (biology)Phosphoinositide 3-kinaseSignalling pathwaysPI3K/AKT/mTOR pathwayConserved sequenceBiology
MeSH terms
AnimalsDictyosteliumDrosophila melanogasterMembrane LipidsMolecular Sequence DataSubstrate SpecificitySignal TransductionCaenorhabditis elegansPhosphotransferases (Alcohol Group Acceptor)Phosphatidylinositol 3-Kinases
Funding
- Vlaamse regering
Citations
945
FWCI
34.16
field-weighted impact
References
52
Percentile
100%
vs. same field & year
Citations per year
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References
Mechanism of activation of protein kinase B by insulin and IGF-1.
The EMBO Journal · 1996 · 3,023 citations
Characterization of a 3-phosphoinositide-dependent protein kinase which phosphorylates and activates protein kinase Bα
Current Biology · 1997 · 2,824 citations
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