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JAK/STAT, Raf/MEK/ERK, PI3K/Akt and BCR-ABL in cell cycle progression and leukemogenesis

Leukemia · 2004 · Vol. 18(2) · pp. 189–218
Linda S. SteelmanSteven C. PohnertJ G SheltonRichard A. FranklinF. E. BertrandJames A. McCubrey
Chronic Myeloid Leukemia TreatmentsQuinazolinone synthesis and applicationsPI3K/AKT/mTOR signaling in cancerMAPK/ERK pathwayCancer researchProtein kinase BGeldanamycinImatinib mesylatePI3K/AKT/mTOR pathwaySignal transductionBiologyABLCell growth

MeSH terms

AnimalsCell CycleHumansLeukemiaProtein KinasesSignal TransductionFusion Proteins, bcr-ablApoptosisReceptors, Cytokine
Citations
685
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18.50
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References
475
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