reviewTop 1% cited
Signal transduction mediated by the Ras/Raf/MEK/ERK pathway from cytokine receptors to transcription factors: potential targeting for therapeutic intervention
Leukemia · 2003 · Vol. 17(7) · pp. 1263–1293
Fuju Chang✉(East Carolina University)Linda S. Steelman(East Carolina University)J T Lee(East Carolina University)J G Shelton(East Carolina University)Patrick M. Navolanic(East Carolina University)William L. Blalock(University of Florida)Richard A. Franklin(East Carolina University)James A. McCubrey(East Carolina University)
Melanoma and MAPK PathwaysSynthesis and biological activityCytokine Signaling Pathways and InteractionsMAPK/ERK pathwaySignal transductionCancer researchAnti-apoptotic Ras signalling cascadeBiologyCell biologyTranscription factorProtein kinase BPI3K/AKT/mTOR pathwayAutocrine signalling
MeSH terms
Enzyme InhibitorsHumansTranscription FactorsDrug DesignReceptors, Cytokineras ProteinsProto-Oncogene Proteins c-rafMAP Kinase Signaling System
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Molecular and Cellular Biology · 1999 · 1,727 citations
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