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PI3K pathway alterations in cancer: variations on a theme

Oncogene · 2008 · Vol. 27(41) · pp. 5497–5510
T L YuanLewis C. Cantley
PI3K/AKT/mTOR signaling in cancerLung Cancer Treatments and MutationsChronic Lymphocytic Leukemia ResearchPTENPI3K/AKT/mTOR pathwayBiologyP110αPhosphoinositide 3-kinaseCancer researchCancerReceptor tyrosine kinaseKinaseProtein kinase B

MeSH terms

Phosphoinositide-3 Kinase InhibitorsAnimalsAntineoplastic Combined Chemotherapy ProtocolsEnzyme InhibitorsHumansModels, BiologicalMutationNeoplasmsNuclear ProteinsGenes, rasTranscription FactorsSignal TransductionGenes, erbB-2Phosphatidylinositol 3-KinasesPTEN Phosphohydrolase
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PI3K pathway alterations in cancer: variations on a theme · Scinovex