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Modulation of NF‐κB‐dependent transcription and cell survival by the SIRT1 deacetylase

The EMBO Journal · 2004 · Vol. 23(12) · pp. 2369–2380
Fan YeungJamie E. HobergC S RamseyMichael D. KellerDavid R. JonesRoy A. FryeMarty W. Mayo
Sirtuins and Resveratrol in MedicineNF-κB Signaling PathwaysGenomics, phytochemicals, and oxidative stressBiologySirtuin 1TransactivationGene silencingSirtuinHistone deacetylaseTranscription factorP300-CBP Transcription FactorsCell biologyCREB-binding protein

MeSH terms

ResveratrolBase SequenceCell SurvivalHistone DeacetylasesHumansStilbenesTranscription, GeneticNF-kappa BDNA PrimersSirtuinsCell Line, TumorSirtuin 1

Funding

  • University of Pennsylvania
  • University of Bern
  • University of North Carolina at Chapel Hill
  • National Cancer Institute
Citations
2,660
FWCI
39.58
field-weighted impact
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53
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100%
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References
Phylogenetic Classification of Prokaryotic and Eukaryotic Sir2-like Proteins
Biochemical and Biophysical Research Communications · 2000 · 1,387 citations
THE NF-κB AND IκB PROTEINS: New Discoveries and Insights
Annual Review of Immunology · 1996 · 5,952 citations
NF-κB at the crossroads of life and death
Nature Immunology · 2002 · 2,690 citations
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