reviewTop 1% cited
Ubiquitination, phosphorylation and acetylation: the molecular basis for p53 regulation
Current Opinion in Cell Biology · 2003 · Vol. 15(2) · pp. 164–171
Christopher Brooks(Cancer Genetics (United States))Wei Gu✉(Columbia University)
Cancer-related Molecular PathwaysUbiquitin and proteasome pathwaysHistone Deacetylase Inhibitors ResearchBiologyAcetylationCell biologyPhosphorylationUbiquitinCarcinogenesisCell growthFunction (biology)SenescenceSuppressor
MeSH terms
AcetylationAnimalsEukaryotic CellsHumansPhosphorylationProtein Processing, Post-TranslationalStress, PhysiologicalTumor Suppressor Protein p53Cell Cycle ProteinsUbiquitin
Funding
- Avon Foundation for Women
- Leukemia and Lymphoma Society
- National Institutes of Health
- National Cancer Institute
Citations
740
FWCI
26.88
field-weighted impact
References
92
Percentile
100%
vs. same field & year
Citations per year
Cited by
Evolutionarily Conserved and Nonconserved Cellular Localizations and Functions of Human SIRT Proteins
Molecular Biology of the Cell · 2005 · 1,354 citations
Sirtuin Functions in Health and Disease
Molecular Endocrinology · 2007 · 473 citations
Identification, analysis, and prediction of protein ubiquitination sites
Proteins Structure Function and Bioinformatics · 2009 · 603 citations
The P53 pathway: what questions remain to be explored?
Cell Death and Differentiation · 2006 · 661 citations
Modulation of NF‐κB‐dependent transcription and cell survival by the SIRT1 deacetylase
The EMBO Journal · 2004 · 2,660 citations
Curcumin as a therapeutic agent: the evidence from<i>in vitro</i>, animal and human studies
British Journal Of Nutrition · 2010 · 459 citations
Substrate and Functional Diversity of Lysine Acetylation Revealed by a Proteomics Survey
Molecular Cell · 2006 · 1,476 citations
References
CBP/p300 in cell growth, transformation, and development
Genes & Development · 2000 · 1,757 citations
Post‐translational modifications and activation of p53 by genotoxic stresses
European Journal of Biochemistry · 2001 · 1,073 citations
p53, the Cellular Gatekeeper for Growth and Division
Cell · 1997 · 7,678 citations
Acetylation: a regulatory modification to rival phosphorylation?
The EMBO Journal · 2000 · 1,150 citations
Regulation and function of the p53 tumor suppressor protein
Current Opinion in Cell Biology · 2001 · 722 citations
Citation Network
How this paper connects to the literature. Drag to explore, click any node to open that paper.