reviewTop 1% cited

NF-κB at the crossroads of life and death

Nature Immunology · 2002 · Vol. 3(3) · pp. 221–227

Michael Karin✉(University of California, San Diego)Anning Lin(University of Chicago)

NF-κB Signaling Pathways Immune Response and Inflammation interferon and immune responsesRegulatorCell biologyTranscription factorProgrammed cell deathImmune systemBiologyApoptosisNF-κBImmunologyCancer research

MeSH terms

AnimalsHumansImmunityProteinsTumor Necrosis Factor-alphaNF-kappa BApoptosisTNF Receptor-Associated Factor 1TNF Receptor-Associated Factor 2Inhibitor of Apoptosis Proteins

Funding

American Cancer Society
National Institutes of Health

Citations

2,690

FWCI

78.34

field-weighted impact

References

Percentile

100%

vs. same field & year

Citations per year

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References

Cutting Edge: Heat Shock Protein 60 Is a Putative Endogenous Ligand of the Toll-Like Receptor-4 Complex

The Journal of Immunology · 2000 · 1,606 citations

IAPs block apoptotic events induced by caspase-8 and cytochrome c by direct inhibition of distinct caspases

The EMBO Journal · 1998 · 1,385 citations

Macrophages that have ingested apoptotic cells in vitro inhibit proinflammatory cytokine production through autocrine/paracrine mechanisms involving TGF-beta, PGE2, and PAF.

Journal of Clinical Investigation · 1998 · 3,128 citations

NF-κB AND REL PROTEINS: Evolutionarily Conserved Mediators of Immune Responses

Annual Review of Immunology · 1998 · 5,171 citations

Phosphorylation Meets Ubiquitination: The Control of NF-κB Activity

Annual Review of Immunology · 2000 · 4,725 citations

Function and Activation of NF-kappaB in the Immune System

Annual Review of Immunology · 1994 · 4,706 citations

Dissecting molecular cross-talk between Nrf2 and NF-κB response pathways

Biochemical Society Transactions · 2015 · 1,094 citations

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