articleTop 1% cited
Thioredoxin-interacting protein links oxidative stress to inflammasome activation
Nature Immunology · 2009 · Vol. 11(2) · pp. 136–140
Rongbin Zhou✉(University of Lausanne)Aubry Tardivel(University of Lausanne)Bernard Thorens(University of Lausanne)Inpyo Choi(Korea Research Institute of Bioscience and Biotechnology)Jürg Tschopp(University of Lausanne)
Inflammasome and immune disordersHeme Oxygenase-1 and Carbon MonoxideAdenosine and Purinergic SignalingTXNIPInflammasomeThioredoxin-Interacting ProteinThioredoxinAIM2Cell biologySignal transducing adaptor proteinReactive oxygen speciesChemistrySignal transduction
MeSH terms
NLR Family, Pyrin Domain-Containing 3 ProteinAnimalsCarrier ProteinsCell LineDiabetes Mellitus, Type 2Enzyme-Linked Immunosorbent AssayGlucoseHumansInflammationThioredoxinsTransfectionImmunoblottingSignal TransductionMice, KnockoutOxidative Stress
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References
Activation of the NALP3 inflammasome is triggered by low intracellular potassium concentration
Cell Death and Differentiation · 2007 · 1,418 citations
The Inflammasomes: Guardians of the Body
Annual Review of Immunology · 2009 · 2,393 citations
The NALP3 inflammasome is involved in the innate immune response to amyloid-β
Nature Immunology · 2008 · 2,375 citations
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Nature Immunology · 2008 · 2,984 citations
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