review Open AccessTop 1% cited
The role of pattern-recognition receptors in innate immunity: update on Toll-like receptors
Nature Immunology · 2010 · Vol. 11(5) · pp. 373–384
Taro Kawai✉(Osaka International University)Shizuo Akira(Osaka University)
Immune Response and InflammationNeutrophil, Myeloperoxidase and Oxidative Mechanismsinterferon and immune responsesInnate immune systemPattern recognition receptorBiologyAcquired immune systemReceptorImmunologyImmune systemImmunityToll-like receptorPathogen-associated molecular pattern
MeSH terms
AnimalsAutoimmune DiseasesHumansImmunity, InnateNucleic AcidsNucleoproteinsSignal TransductionToll-Like ReceptorsHost-Pathogen InteractionsAdaptive Immunity
Funding
- Ministry of Education, Culture, Sports, Science and Technology
- National Institutes of Health
Citations
8,950
FWCI
194.30
field-weighted impact
References
137
Percentile
100%
vs. same field & year
Citations per year
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References
Toll-like receptors: critical proteins linking innate and acquired immunity
Nature Immunology · 2001 · 4,755 citations
The inflammasome: a caspase-1-activation platform that regulates immune responses and disease pathogenesis
Nature Immunology · 2009 · 1,825 citations
Pathogen Recognition and Innate Immunity
Cell · 2006 · 11,743 citations
Heat shock proteins and immune system
Journal of Leukocyte Biology · 2009 · 465 citations
Toll‐like Receptor and RIG‐1‐like Receptor Signaling
Annals of the New York Academy of Sciences · 2008 · 965 citations
CD36 ligands promote sterile inflammation through assembly of a Toll-like receptor 4 and 6 heterodimer
Nature Immunology · 2009 · 1,484 citations
Innate immune recognition of viral infection
Nature Immunology · 2006 · 1,871 citations
NF-κB-dependent induction of microRNA miR-146, an inhibitor targeted to signaling proteins of innate immune responses
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