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Immunosuppression in sepsis: a novel understanding of the disorder and a new therapeutic approach

The Lancet Infectious Diseases · 2013 · Vol. 13(3) · pp. 260–268
Richard S. HotchkissGuillaume MonneretDidier Payen
Immune Response and InflammationSepsis Diagnosis and TreatmentNeuroinflammation and Neurodegeneration MechanismsSepsisImmunosuppressionMedicineImmunologyClinical trialIntensive care medicineImmunityImmune systemInternal medicine

MeSH terms

HumansImmunologic FactorsInterleukin-7Granulocyte-Macrophage Colony-Stimulating FactorCytokinesImmunocompromised HostSepsisImmunomodulationB7-H1 AntigenProgrammed Cell Death 1 Receptor
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References
Improved Survival with Ipilimumab in Patients with Metastatic Melanoma
New England Journal of Medicine · 2010 · 15,037 citations
The effect of age on the development and outcome of adult sepsis*
Critical Care Medicine · 2005 · 1,051 citations
PD-1 and Its Ligands in Tolerance and Immunity
Annual Review of Immunology · 2008 · 5,272 citations
Safety, Activity, and Immune Correlates of Anti–PD-1 Antibody in Cancer
New England Journal of Medicine · 2012 · 12,531 citations
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