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The effect of age on the development and outcome of adult sepsis*
Critical Care Medicine · 2005 · Vol. 34(1) · pp. 15–21
Abstract
The incidence of sepsis is disproportionately increased in elderly adults, and age is an independent predictor of mortality. Compared with younger sepsis patients, elderly nonsurvivors of sepsis die earlier during hospitalization and elderly survivors more frequently require skilled nursing or rehabilitative care after hospitalization. These findings have implications for patient care and health care resource prioritization and provide insights for expanded scientific investigations and potential patient interventions.
Sepsis Diagnosis and TreatmentNosocomial Infections in ICUHemodynamic Monitoring and TherapyMedicineConfidence intervalSepsisOdds ratioIncidence (geometry)Case fatality rateRelative riskPneumoniaInternal medicineEpidemiology
MeSH terms
AdultAgedAged, 80 and overCause of DeathCritical CareFemaleHumansIntensive Care UnitsLongitudinal StudiesMaleMiddle AgedProbabilityRetrospective StudiesUnited StatesIncidence
Citations
1,051
FWCI
10.34
field-weighted impact
References
48
Percentile
99%
vs. same field & year
Citations per year
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References
The APACHE III Prognostic System
CHEST Journal · 1992 · 2,897 citations
Epidemiology of severe sepsis in the United States: Analysis of incidence, outcome, and associated costs of care
Critical Care Medicine · 2001 · 8,573 citations
The APACHE III Prognostic System
CHEST Journal · 1991 · 3,455 citations
Adapting a clinical comorbidity index for use with ICD-9-CM administrative databases
Journal of Clinical Epidemiology · 1992 · 10,478 citations
Validation of a combined comorbidity index
Journal of Clinical Epidemiology · 1994 · 6,512 citations
Surviving Sepsis Campaign guidelines for management of severe sepsis and septic shock
Intensive Care Medicine · 2004 · 3,341 citations
EPISEPSIS: a reappraisal of the epidemiology and outcome of severe sepsis in French intensive care units
Intensive Care Medicine · 2004 · 635 citations
Surviving Sepsis Campaign Management Guidelines Committee. Surviving Sepsis Campaign guidelines for management of severe sepsis and septic shock
Critical Care Medicine · 2004 · 1,852 citations
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