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Sepsis-induced immunosuppression: from cellular dysfunctions to immunotherapy

Nature reviews. Immunology · 2013 · Vol. 13(12) · pp. 862–874
Richard S. HotchkissGuillaume MonneretDidier Payen
Immune Response and InflammationSepsis Diagnosis and TreatmentVitamin C and Antioxidants ResearchSepsisImmunosuppressionImmunologyMedicineImmune systemImmunotherapyOrgan dysfunctionDiseaseBiomarkerImmune Dysfunction

MeSH terms

AnimalsHumansImmune ToleranceImmunity, CellularImmunity, InnateImmunotherapyInflammationSepsisModels, AnimalMice

Funding

  • University of Washington
  • Hospices Civils de Lyon
  • National Institutes of Health
Citations
2,562
FWCI
45.08
field-weighted impact
References
178
Percentile
100%
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Citations per year
References
Immunity to fungal infections
Nature reviews. Immunology · 2011 · 1,787 citations
Improved Survival with Ipilimumab in Patients with Metastatic Melanoma
New England Journal of Medicine · 2010 · 15,037 citations
Of Mice and Not Men: Differences between Mouse and Human Immunology
The Journal of Immunology · 2004 · 3,699 citations
T cell exhaustion
Nature Immunology · 2011 · 3,925 citations
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