review Open AccessTop 1% cited
The immunopathology of sepsis and potential therapeutic targets
Nature reviews. Immunology · 2017 · Vol. 17(7) · pp. 407–420
Tom van der Poll✉(University of Amsterdam)Frank L. van de Veerdonk(Radboud University Medical Center)Brendon P. Scicluna(University of Amsterdam)Mihai G. Netea(Radboud University Medical Center)
Sepsis Diagnosis and TreatmentImmune Response and InflammationInflammation biomarkers and pathwaysSepsisPathogenesisImmune systemImmunologyInflammationPathologicalMedicineImmunopathologyHost responseBiology
MeSH terms
AnimalsBacterial InfectionsHumansTranscription, GeneticSepsisEpigenomicsMicrobiota
Citations
1,858
FWCI
79.21
field-weighted impact
References
143
Percentile
100%
vs. same field & year
Citations per year
Cited by
Interleukin‐18: Biological properties and role in disease pathogenesis
Immunological Reviews · 2017 · 583 citations
Pathological alteration and therapeutic implications of sepsis-induced immune cell apoptosis
Cell Death and Disease · 2019 · 371 citations
Pathological inflammation in patients with COVID-19: a key role for monocytes and macrophages
Nature reviews. Immunology · 2020 · 2,572 citations
References
Complement System Part II: Role in Immunity
Frontiers in Immunology · 2015 · 1,003 citations
The SOFA (Sepsis-related Organ Failure Assessment) score to describe organ dysfunction/failure
Intensive Care Medicine · 1996 · 11,451 citations
Mechanisms of post-transcriptional regulation by microRNAs: are the answers in sight?
Nature Reviews Genetics · 2008 · 5,192 citations
Pattern Recognition Receptors and Inflammation
Cell · 2010 · 8,539 citations
Thrombosis as an intravascular effector of innate immunity
Nature reviews. Immunology · 2012 · 1,828 citations
Sepsis-induced immunosuppression: from cellular dysfunctions to immunotherapy
Nature reviews. Immunology · 2013 · 2,562 citations
2001 SCCM/ESICM/ACCP/ATS/SIS International Sepsis Definitions Conference
Critical Care Medicine · 2003 · 5,994 citations
Benchmarking the Incidence and Mortality of Severe Sepsis in the United States*
Critical Care Medicine · 2013 · 1,343 citations
Citation Network
How this paper connects to the literature. Drag to explore, click any node to open that paper.
