reviewTop 1% cited
T cell exhaustion
Nature Immunology · 2011 · Vol. 12(6) · pp. 492–499
E. John Wherry✉(University of Pennsylvania)
Immune Cell Function and InteractionT-cell and B-cell ImmunologyCancer Immunotherapy and BiomarkersEffectorBiologyPhenotypeCellFunction (biology)Cell functionT cellImmunologyReceptorCell biology
MeSH terms
AnimalsBacterial InfectionsHumansImmunologic MemoryT-LymphocytesVirus DiseasesCytokinesCD8-Positive T-LymphocytesModels, ImmunologicalInflammation Mediators
Citations
3,925
FWCI
55.95
field-weighted impact
References
118
Percentile
100%
vs. same field & year
Citations per year
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References
Ido expression by dendritic cells: tolerance and tryptophan catabolism
Nature reviews. Immunology · 2004 · 2,302 citations
Phase I Study of Single-Agent Anti–Programmed Death-1 (MDX-1106) in Refractory Solid Tumors: Safety, Clinical Activity, Pharmacodynamics, and Immunologic Correlates
Journal of Clinical Oncology · 2010 · 2,913 citations
Molecular Signature of CD8+ T Cell Exhaustion during Chronic Viral Infection
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Coregulation of CD8+ T cell exhaustion by multiple inhibitory receptors during chronic viral infection
Nature Immunology · 2008 · 2,037 citations
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The Journal of Experimental Medicine · 2010 · 2,039 citations
T Cell Anergy
Annual Review of Immunology · 2003 · 1,443 citations
Alternative Activation of Macrophages: An Immunologic Functional Perspective
Annual Review of Immunology · 2008 · 2,725 citations
SHP-1 and SHP-2 Associate with Immunoreceptor Tyrosine-Based Switch Motif of Programmed Death 1 upon Primary Human T Cell Stimulation, but Only Receptor Ligation Prevents T Cell Activation
The Journal of Immunology · 2004 · 1,218 citations
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