article Open AccessTop 1% cited
The NAD+ Precursor Nicotinamide Riboside Enhances Oxidative Metabolism and Protects against High-Fat Diet-Induced Obesity
Cell Metabolism · 2012 · Vol. 15(6) · pp. 838–847
Carles Cantó(École Polytechnique Fédérale de Lausanne)Riekelt H. Houtkooper(École Polytechnique Fédérale de Lausanne)Eija Pirinen(University of Eastern Finland)Dou Yeon Youn(Cornell University)Maaike H. Oosterveer(École Polytechnique Fédérale de Lausanne)Yana Cen(Cornell University)Pablo J. Fernández-Marcos(École Polytechnique Fédérale de Lausanne)Hiroyasu Yamamoto(École Polytechnique Fédérale de Lausanne)Pénélope A. Andreux(École Polytechnique Fédérale de Lausanne)Philippe Cettour-Rose(École Polytechnique Fédérale de Lausanne)Karl Gademann(University of Basel)Chris Rinsch(Amazentis (Switzerland))Kristina Schoonjans(École Polytechnique Fédérale de Lausanne)Anthony A. Sauve(Cornell University)Johan Auwerx✉(École Polytechnique Fédérale de Lausanne)
Sirtuins and Resveratrol in MedicineCalcium signaling and nucleotide metabolismAdipose Tissue and MetabolismNAD+ kinaseOxidative phosphorylationNicotinamideOxidative metabolismMetabolismChemistryEnergy metabolismBiochemistryEndocrinologyMedicine
MeSH terms
Superoxide Dismutase 2AcetylationAnimalsBrainAdipose Tissue, BrownEnergy MetabolismHumansLiverMaleMice, Inbred C57BLMitochondriaNADNiacinamideObesityOrgan Specificity
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References
The Human Sir2 Ortholog, SIRT2, Is an NAD+-Dependent Tubulin Deacetylase
Molecular Cell · 2003 · 1,517 citations
The FoxO code
Oncogene · 2008 · 1,151 citations
Nicotinamide Mononucleotide, a Key NAD+ Intermediate, Treats the Pathophysiology of Diet- and Age-Induced Diabetes in Mice
Cell Metabolism · 2011 · 1,317 citations
Calorie Restriction Reduces Oxidative Stress by SIRT3-Mediated SOD2 Activation
Cell Metabolism · 2010 · 1,295 citations
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