article Open AccessTop 1% cited
Calorie Restriction Reduces Oxidative Stress by SIRT3-Mediated SOD2 Activation
Cell Metabolism · 2010 · Vol. 12(6) · pp. 662–667
Xiaolei Qiu✉(University of California, Berkeley)Katharine Brown(University of California, Berkeley)Matthew D. Hirschey(University of California, San Francisco)Eric Verdin(University of California, San Francisco)Danica Chen(University of California, Berkeley)
Sirtuins and Resveratrol in MedicineGenetics, Aging, and Longevity in Model OrganismsAdipose Tissue and MetabolismSOD2SIRT3Oxidative stressReactive oxygen speciesSuperoxide dismutaseCalorie restrictionMitochondrial ROSAntioxidantMitochondrionOxidative phosphorylation
MeSH terms
Superoxide Dismutase 2AcetylationAnimalsCell SurvivalDose-Response Relationship, DrugEnzyme ActivationFlow CytometryGlutathioneNitroblue TetrazoliumParaquatSuperoxide DismutaseReactive Oxygen SpeciesMice, KnockoutOxidative StressCaloric Restriction
Funding
- Searle Scholars Program
Citations
1,295
FWCI
28.22
field-weighted impact
References
42
Percentile
100%
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Citations per year
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References
Substrate and Functional Diversity of Lysine Acetylation Revealed by a Proteomics Survey
Molecular Cell · 2006 · 1,476 citations
Phylogenetic Classification of Prokaryotic and Eukaryotic Sir2-like Proteins
Biochemical and Biophysical Research Communications · 2000 · 1,387 citations
Glucose Restriction Extends Caenorhabditis elegans Life Span by Inducing Mitochondrial Respiration and Increasing Oxidative Stress
Cell Metabolism · 2007 · 1,203 citations
Is the oxidative stress theory of aging dead?
Biochimica et Biophysica Acta (BBA) - General Subjects · 2009 · 599 citations
Mammalian Sir2 Homolog SIRT3 Regulates Global Mitochondrial Lysine Acetylation
Molecular and Cellular Biology · 2007 · 1,209 citations
The SIR2/3/4 complex and SIR2 alone promote longevity in Saccharomyces cerevisiae by two different mechanisms
Genes & Development · 1999 · 2,256 citations
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