article Open AccessTop 1% cited
Nicotinamide Mononucleotide, a Key NAD+ Intermediate, Treats the Pathophysiology of Diet- and Age-Induced Diabetes in Mice
Cell Metabolism · 2011 · Vol. 14(4) · pp. 528–536
Jun Yoshino(Washington University in St. Louis)Kathryn F. Mills(Washington University in St. Louis)Myeong Jin Yoon(Washington University in St. Louis)Shin‐ichiro Imai✉(Washington University in St. Louis)
Sirtuins and Resveratrol in MedicineAdipose Tissue and MetabolismCalcium signaling and nucleotide metabolismNicotinamide mononucleotideNAD+ kinaseDiabetes mellitusPathophysiologyNicotinamideMedicineInternal medicineEndocrinologyGerontologyChemistry
MeSH terms
AgingAnimalsCircadian RhythmDiabetes Mellitus, Type 2Disease Models, AnimalGene Expression RegulationGlucoseHypoglycemic AgentsInsulinNADNicotinamide MononucleotideCytokinesOxidative StressLipid MetabolismMice
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References
Glucose Restriction Inhibits Skeletal Myoblast Differentiation by Activating SIRT1 through AMPK-Mediated Regulation of Nampt
Developmental Cell · 2008 · 802 citations
Modulation of NF‐κB‐dependent transcription and cell survival by the SIRT1 deacetylase
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