reviewTop 1% cited

Drug penetration in solid tumours

Nature reviews. Cancer · 2006 · Vol. 6(8) · pp. 583–592

Andrew I. Minchinton✉(BC Cancer Agency)Ian F. Tannock(University of Toronto)

Cancer Cells and Metastasis HER2/EGFR in Cancer Research Nanoparticle-Based Drug DeliveryDrugDrug resistanceCancer chemotherapyPenetration (warfare)Distribution (mathematics)Tumour tissuePopulationCancer researchPharmacologyTherapeutic index

MeSH terms

AnimalsAntineoplastic AgentsHumansNeoplasmsTumor Cells, CulturedDrug Delivery SystemsSpheroids, CellularDrug Resistance, Neoplasm

Citations

2,726

FWCI

26.37

field-weighted impact

References

150

Percentile

100%

vs. same field & year

Citations per year

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References

Hypoxia — a key regulatory factor in tumour growth

Nature reviews. Cancer · 2002 · 5,147 citations

Vascular Normalization by Vascular Endothelial Growth Factor Receptor 2 Blockade Induces a Pressure Gradient Across the Vasculature and Improves Drug Penetration in Tumors

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The relation between cell proliferation and the vascular system in a transplanted mouse mammary tumour

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Openings between Defective Endothelial Cells Explain Tumor Vessel Leakiness

American Journal Of Pathology · 2000 · 1,663 citations

High interstitial fluid pressure — an obstacle in cancer therapy

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The Histological Structure of Some Human Lung Cancers and the Possible Implications for Radiotherapy

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