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Health Sciences → Medicine → Oncology

HER2/EGFR in Cancer Research

This cluster of papers focuses on the use of HER2-targeted therapies, such as trastuzumab and pertuzumab, in the treatment of HER2-positive breast cancer. It explores the mechanisms of action, resistance, and combination therapies involving chemotherapy and monoclonal antibodies. The cluster also delves into the role of EGFR, neuregulin 1, and ADAM metalloproteinases in HER2 signaling and breast cancer progression.

67.7K works worldwide1.3M citations
HER2breast cancertrastuzumabEGFRmonoclonal antibodychemotherapymetastaticreceptor tyrosine kinasesneuregulin 1ADAM metalloproteinases

Journals publishing in this area

1
Journal of Clinical Oncology
ISSN 0732-183X5,893 articles in this topic
733h-index
2Cancer Research cover
Cancer Research
ISSN 0008-54725,623 articles in this topic
465h-index
3Annals of Oncology cover
Annals of Oncology
ISSN 0923-75343,390 articles in this topic
384h-index
4
Breast Cancer Research and Treatment
ISSN 0167-68061,755 articles in this topic
219h-index
5Clinical Cancer Research cover
Clinical Cancer Research
ISSN 1078-04321,704 articles in this topic
417h-index
6European Journal of Cancer cover
European Journal of Cancer
ISSN 0959-80491,596 articles in this topic
295h-index
7British Journal of Cancer cover
British Journal of Cancer
ISSN 0007-0920888 articles in this topic
344h-index
8The Lancet Oncology cover
The Lancet Oncology
ISSN 1470-2045409 articles in this topic
511h-index
9International Journal of Orthopaedics and Rheumatology cover
International Journal of Orthopaedics and Rheumatology
ISSN 2664-96911 articles in this topic
1h-index