reviewTop 1% cited
High interstitial fluid pressure — an obstacle in cancer therapy
Nature reviews. Cancer · 2004 · Vol. 4(10) · pp. 806–813
Carl‐Henrik Heldin✉(Ludwig Cancer Research)Kristofer Rubin(Uppsala University)Kristian Pietras(University of California, San Francisco)Arne Östman(Karolinska Institutet)
Lymphatic System and DiseasesAngiogenesis and VEGF in CancerCancer Treatment and PharmacologyInterstitial fluidCancer researchMedicineCancer treatmentFibrosisContraction (grammar)ChemistryCancerPathologyInternal medicine
MeSH terms
AlprostadilAnimalsAntineoplastic AgentsBiological TransportBradykininHumansHyaluronoglucosaminidaseHydrostatic PressureNeoplasmsNiacinamidePlatelet-Derived Growth FactorTumor Necrosis Factor-alphaSignal TransductionTransforming Growth Factor betaVascular Endothelial Growth Factor A
Funding
- Cancerfonden
Citations
2,134
FWCI
15.01
field-weighted impact
References
81
Percentile
99%
vs. same field & year
Citations per year
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References
Vascular Normalization by Vascular Endothelial Growth Factor Receptor 2 Blockade Induces a Pressure Gradient Across the Vasculature and Improves Drug Penetration in Tumors
Cancer Research · 2004 · 1,179 citations
Abnormalities in Pericytes on Blood Vessels and Endothelial Sprouts in Tumors
American Journal Of Pathology · 2002 · 970 citations
The myofibroblast in wound healing and fibrocontractive diseases
The Journal of Pathology · 2003 · 1,598 citations
Inhibition of Vascular Endothelial Growth Factor (VEGF) Signaling in Cancer Causes Loss of Endothelial Fenestrations, Regression of Tumor Vessels, and Appearance of Basement Membrane Ghosts
American Journal Of Pathology · 2004 · 757 citations
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