articleTop 1% cited
Spheroid-based drug screen: considerations and practical approach
Nature Protocols · 2009 · Vol. 4(3) · pp. 309–324
Juergen Friedrich✉(University of Regensburg)Claudia Seidel(OncoRay)Reinhard Ebner(Avalon Pharma (United States))Leoni A. Kunz‐Schughart(University Hospital Carl Gustav Carus)
Cancer Cells and Metastasis3D Printing in Biomedical ResearchCellular Mechanics and InteractionsSpheroidDrugComputational biology3D cell cultureCell cultureAnticancer drugComputer scienceDrug developmentBiologyBioinformatics
MeSH terms
Antineoplastic AgentsDrug Screening Assays, AntitumorHumansSpheroids, CellularCell Line, Tumor
Funding
- Bundesministerium für Bildung und Forschung
Citations
1,670
FWCI
18.16
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References
94
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100%
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References
Three-dimensional cell cultures: from molecular mechanisms to clinical applications
American Journal of Physiology-Cell Physiology · 1997 · 535 citations
CD133: molecule of the moment
The Journal of Pathology · 2007 · 521 citations
Drug penetration in solid tumours
Nature reviews. Cancer · 2006 · 2,726 citations
Distinct Populations of Cancer Stem Cells Determine Tumor Growth and Metastatic Activity in Human Pancreatic Cancer
Cell stem cell · 2007 · 2,914 citations
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