reviewTop 10% cited
Lyophilization and development of solid protein pharmaceuticals
International Journal of Pharmaceutics · 2000 · Vol. 203(1-2) · pp. 1–60
Wei Wang✉(Bayer (United States))
Protein purification and stabilityTransgenic Plants and ApplicationsGlycosylation and Glycoproteins ResearchProtein stabilityDenaturation (fissile materials)Biochemical engineeringFreeze-dryingChemistryNanotechnologyBiotechnologyMaterials scienceChromatographyEngineering
MeSH terms
CarbohydratesChemistry, PharmaceuticalFreeze DryingHydrogen-Ion ConcentrationPolymersProtein DenaturationProteinsTemperature
Citations
1,143
FWCI
3.30
field-weighted impact
References
299
Percentile
93%
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References
Rational Design of Stable Lyophilized Protein Formulations: Some Practical Advice
Pharmaceutical Research · 1997 · 671 citations
Stability of Protein Pharmaceuticals
Pharmaceutical Research · 1989 · 1,072 citations
Molecular Mobility of Amorphous Pharmaceutical Solids Below Their Glass Transition Temperatures
Pharmaceutical Research · 1995 · 878 citations
The Relationship Between the Glass Transition Temperature and the Water Content of Amorphous Pharmaceutical Solids
Pharmaceutical Research · 1994 · 701 citations
Infrared Spectroscopic Studies of Lyophilization‐ and Temperature‐Induced Protein Aggregation
Journal of Pharmaceutical Sciences · 1995 · 457 citations
Hydrogen Bonding between Sugar and Protein Is Responsible for Inhibition of Dehydration-Induced Protein Unfolding
Archives of Biochemistry and Biophysics · 1999 · 535 citations
Effect of Mannitol Crystallinity on the Stabilization of Enzymes during Freeze-Drying.
Chemical and Pharmaceutical Bulletin · 1994 · 165 citations
Melting and glass transitions of low molecular weight carbohydrates
Carbohydrate Research · 1993 · 597 citations
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