article Open AccessTop 1% cited
Nrf2 Redirects Glucose and Glutamine into Anabolic Pathways in Metabolic Reprogramming
Cancer Cell · 2012 · Vol. 22(1) · pp. 66–79
Yoichiro Mitsuishi(Tohoku University)Keiko Taguchi(Tohoku University)Yukie Kawatani(Tohoku University)Tatsuhiro ShibataToshihiro Nukiwa(Tohoku University)Hiroyuki Aburatani(The University of Tokyo)Masayuki Yamamoto✉(Tohoku University)Hozumi Motohashi✉(Tohoku University)
Genomics, phytochemicals, and oxidative stressGlutathione Transferases and PolymorphismsBiochemical Acid Research StudiesAnabolismPI3K/AKT/mTOR pathwayCytoprotectionReprogrammingCell biologyProtein kinase BRegulatorGlutamineBiologyCell growth
MeSH terms
AnimalsCell DivisionGlucoseGlutamineMice, TransgenicNeoplasmsSignal TransductionPhosphatidylinositol 3-KinasesProto-Oncogene Proteins c-aktNF-E2-Related Factor 2Mice
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An Nrf2/Small Maf Heterodimer Mediates the Induction of Phase II Detoxifying Enzyme Genes through Antioxidant Response Elements
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Akt Stimulates Aerobic Glycolysis in Cancer Cells
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