reviewTop 1% cited
Regulation of Nrf2—an update
Free Radical Biology and Medicine · 2013 · Vol. 66 · pp. 36–44
Suryakant Niture(University of Maryland, Baltimore)Raju Khatri(University of Maryland, Baltimore)Anil K. Jaiswal✉
Genomics, phytochemicals, and oxidative stressFamily Support in IllnessGlutathione Transferases and PolymorphismsBusiness
MeSH terms
Kelch-Like ECH-Associated Protein 1AnimalsAntioxidantsHumansNeoplasmsSignal TransductionTranscriptional ActivationOxidative StressDrug Resistance, Neoplasmalpha-TocopherolIntracellular Signaling Peptides and ProteinsNF-E2-Related Factor 2Carcinogenesis
Funding
- National Institutes of Health
Citations
851
FWCI
29.45
field-weighted impact
References
130
Percentile
100%
vs. same field & year
Citations per year
Cited by
An Overview of Nrf2 Signaling Pathway and Its Role in Inflammation
Molecules · 2020 · 1,266 citations
The role of Nrf2 in oxidative stress-induced endothelial injuries
Journal of Endocrinology · 2015 · 398 citations
Diabetic Cardiomyopathy
Circulation Research · 2018 · 1,717 citations
References
NRF2 and KEAP1 mutations: permanent activation of an adaptive response in cancer
Trends in Biochemical Sciences · 2009 · 863 citations
Nrf2 Redirects Glucose and Glutamine into Anabolic Pathways in Metabolic Reprogramming
Cancer Cell · 2012 · 1,350 citations
Nrf2 signaling in coordinated activation of antioxidant gene expression
Free Radical Biology and Medicine · 2004 · 1,236 citations
The selective autophagy substrate p62 activates the stress responsive transcription factor Nrf2 through inactivation of Keap1
Nature Cell Biology · 2010 · 2,361 citations
Keap1 represses nuclear activation of antioxidant responsive elements by Nrf2 through binding to the amino-terminal Neh2 domain
Genes & Development · 1999 · 3,543 citations
Curcumin activates the haem oxygenase-1 gene via regulation of Nrf2 and the antioxidant-responsive element
Biochemical Journal · 2003 · 1,018 citations
Distinct Cysteine Residues in Keap1 Are Required for Keap1-Dependent Ubiquitination of Nrf2 and for Stabilization of Nrf2 by Chemopreventive Agents and Oxidative Stress
Molecular and Cellular Biology · 2003 · 1,425 citations
The Keap1-BTB Protein Is an Adaptor That Bridges Nrf2 to a Cul3-Based E3 Ligase: Oxidative Stress Sensing by a Cul3-Keap1 Ligase
Molecular and Cellular Biology · 2004 · 967 citations
Citation Network
How this paper connects to the literature. Drag to explore, click any node to open that paper.