reviewTop 1% cited
Multidrug resistance proteins: role of P-glycoprotein, MRP1, MRP2, and BCRP (ABCG2) in tissue defense
Toxicology and Applied Pharmacology · 2004 · Vol. 204(3) · pp. 216–237
Elaine M. Leslie(University of North Carolina at Chapel Hill)Roger G. Deeley(Queen's University)Susan P.C. Cole✉(Queen's University)
Drug Transport and Resistance MechanismsPharmacological Effects and Toxicity StudiesTrace Elements in HealthAbcg2Multidrug resistance-associated protein 2ATP-binding cassette transporterP-glycoproteinABCC1Multidrug Resistance-Associated ProteinsEffluxTransporterBiologyDrug metabolism
MeSH terms
ATP Binding Cassette Transporter, Subfamily G, Member 2Multidrug Resistance-Associated Protein 2AnimalsFemaleHumansNeoplasm ProteinsPregnancyTissue DistributionATP Binding Cassette Transporter, Subfamily BATP-Binding Cassette TransportersATP Binding Cassette Transporter, Subfamily B, Member 1Membrane Transport ProteinsMultidrug Resistance-Associated ProteinsATP-Binding Cassette, Sub-Family C ProteinsDrug-Related Side Effects and Adverse Reactions
Citations
1,406
FWCI
25.17
field-weighted impact
References
257
Percentile
100%
vs. same field & year
Citations per year
Cited by
Glutathione in Cancer Cell Death
Cancers · 2011 · 307 citations
NRF2 and KEAP1 mutations: permanent activation of an adaptive response in cancer
Trends in Biochemical Sciences · 2009 · 863 citations
The zebrafish embryo model in environmental risk assessment—applications beyond acute toxicity testing
Environmental Science and Pollution Research · 2008 · 587 citations
Cancer Statistics, 2006
CA A Cancer Journal for Clinicians · 2006 · 5,336 citations
Targeting multidrug resistance in cancer
Nature Reviews Drug Discovery · 2006 · 3,630 citations
References
Distantly related sequences in the alpha- and beta-subunits of ATP synthase, myosin, kinases and other ATP-requiring enzymes and a common nucleotide binding fold.
The EMBO Journal · 1982 · 5,305 citations
Drug Resistance and ATP-Dependent Conjugate Transport Mediated by the Apical Multidrug Resistance Protein, MRP2, Permanently Expressed in Human and Canine Cells
Molecular Pharmacology · 1999 · 680 citations
Localisation of breast cancer resistance protein in microvessel endothelium of human brain
Neuroreport · 2002 · 407 citations
Importance of P-glycoprotein at blood–tissue barriers
Trends in Pharmacological Sciences · 2004 · 582 citations
An inventory of the human ABC proteins
Biochimica et Biophysica Acta (BBA) - Biomembranes · 1999 · 580 citations
Related articles
Multidrug resistance proteins: role of P-glycoprotein, MRP1, MRP2, and BCRP (ABCG2) in tissue defense
Toxicology and Applied Pharmacology · 2004 · 1,406 citations
Citation Network
How this paper connects to the literature. Drag to explore, click any node to open that paper.