reviewTop 1% cited
Multidrug resistance in cancer: role of ATP–dependent transporters
Nature reviews. Cancer · 2002 · Vol. 2(1) · pp. 48–58
Michael M. Gottesman✉(Office of the Director)Tito Fojo(National Institutes of Health)Susan E. Bates(National Institutes of Health)
Drug Transport and Resistance MechanismsCancer therapeutics and mechanismsCholangiocarcinoma and Gallbladder Cancer StudiesMultiple drug resistanceChemotherapyDrug resistanceCancerCancer chemotherapyCancer cellATP-binding cassette transporterDrugCancer drugsMedicine
MeSH terms
Adenosine TriphosphateAntineoplastic AgentsBreast NeoplasmsFemaleForecastingMultigene FamilyHumansLeukemiaNeoplasm ProteinsNeoplasmsOrgan SpecificityPermeabilityStructure-Activity RelationshipDrug DesignXenobiotics
Citations
5,468
FWCI
58.77
field-weighted impact
References
171
Percentile
100%
vs. same field & year
Citations per year
Cited by
Targeting Epithelial–Mesenchymal Transition (EMT) to Overcome Drug Resistance in Cancer
Molecules · 2016 · 810 citations
Drug Resistance in Leishmaniasis
Clinical Microbiology Reviews · 2006 · 1,652 citations
Glutathione in Cancer Cell Death
Cancers · 2011 · 307 citations
Drug Resistance in Cancer: An Overview
Cancers · 2014 · 2,424 citations
Epithelial Mesenchymal Transition in Embryonic Development, Tissue Repair and Cancer: A Comprehensive Overview
Journal of Clinical Medicine · 2017 · 297 citations
Tumour stem cells and drug resistance
Nature reviews. Cancer · 2005 · 3,647 citations
Therapeutic Nanoparticles for Drug Delivery in Cancer
Clinical Cancer Research · 2008 · 2,887 citations
Mesoporous Silica Nanoparticles: Synthesis, Biocompatibility and Drug Delivery
Advanced Materials · 2012 · 2,771 citations
References
Modulators and substrates of P-glycoprotein and cytochrome P4503A coordinately up-regulate these proteins in human colon carcinoma cells.
Molecular Pharmacology · 1996 · 497 citations
Conjugate export pumps of the multidrug resistance protein (MRP) family: localization, substrate specificity, and MRP2-mediated drug resistance
Biochimica et Biophysica Acta (BBA) - Biomembranes · 1999 · 801 citations
Active outward transport of daunomycin in resistant ehrlich ascites tumor cells
Biochimica et Biophysica Acta (BBA) - Biomembranes · 1973 · 725 citations
Role of intestinal P-glycoprotein (mdr1) in interpatient variation in the oral bioavailability of cyclosporine*
Clinical Pharmacology & Therapeutics · 1997 · 683 citations
Expression of Multidrug Resistance Gene in Human Cancers
JNCI Journal of the National Cancer Institute · 1989 · 1,297 citations
A surface glycoprotein modulating drug permeability in Chinese hamster ovary cell mutants
Biochimica et Biophysica Acta (BBA) - Biomembranes · 1976 · 3,268 citations
Expression of the multidrug resistance gene product (P-glycoprotein) in human normal and tumor tissues.
Journal of Histochemistry & Cytochemistry · 1990 · 1,070 citations
The Human ATP-Binding Cassette (ABC) Transporter Superfamily
Genome Research · 2001 · 1,739 citations
Citation Network
How this paper connects to the literature. Drag to explore, click any node to open that paper.
