reviewTop 1% cited
The CD95 (APO-1/Fas) and the TRAIL (APO-2L) Apoptosis Systems
Experimental Cell Research · 2000 · Vol. 256(1) · pp. 58–66
Henning Walczak✉Peter H. Krammer(Heidelberg University)
RNA Interference and Gene DeliveryCell death mechanisms and regulationImmunotherapy and Immune ResponsesBiologyCancer cellPeptideCancerCytotoxicityIn vivoApoptosisCancer researchFas receptorCell
MeSH terms
AnimalsHumansLiverMembrane GlycoproteinsT-LymphocytesTumor Necrosis Factor-alphaApoptosisfas ReceptorApoptosis Regulatory ProteinsTNF-Related Apoptosis-Inducing LigandFas Ligand Protein
Citations
625
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104
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References
Tumoricidal activity of tumor necrosis factor–related apoptosis–inducing ligand in vivo
Nature Medicine · 1999 · 2,493 citations
Cytotoxicity-dependent APO-1 (Fas/CD95)-associated proteins form a death-inducing signaling complex (DISC) with the receptor.
The EMBO Journal · 1995 · 2,138 citations
Two CD95 (APO-1/Fas) signaling pathways
The EMBO Journal · 1998 · 2,997 citations
FLICE is activated by association with the CD95 death-inducing signaling complex (DISC)
The EMBO Journal · 1997 · 1,191 citations
Cleavage of BID by Caspase 8 Mediates the Mitochondrial Damage in the Fas Pathway of Apoptosis
Cell · 1998 · 4,423 citations
Safety and antitumor activity of recombinant soluble Apo2 ligand
Journal of Clinical Investigation · 1999 · 2,210 citations
Identification and characterization of a new member of the TNF family that induces apoptosis
Immunity · 1995 · 2,891 citations
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