articleTop 1% cited
IL-6 programs TH-17 cell differentiation by promoting sequential engagement of the IL-21 and IL-23 pathways
Nature Immunology · 2007 · Vol. 8(9) · pp. 967–974
Liang Zhou✉(New York University)Ivaylo I. Ivanov(New York University)Rosanne Spolski(National Heart Lung and Blood Institute)Roy Min(New York University)Kevin Shenderov(New York University)Takeshi Egawa(New York University)David T. Levy(New York University)Warren J. Leonard(National Heart Lung and Blood Institute)Dan R. Littman(New York University)
Psoriasis: Treatment and PathogenesisWhipple's Disease and InterleukinsCytokine Signaling Pathways and InteractionsAutocrine signallingRAR-related orphan receptor gammaCell biologyInterleukin 17BiologyCytokineSTAT3Cellular differentiationTranscription factorInterleukin 9
MeSH terms
Interleukin-21AnimalsCell DifferentiationCells, CulturedFlow CytometryT-Lymphocytes, Helper-InducerInterleukinsMice, Mutant StrainsReceptors, Thyroid HormoneRNA, MessengerImmunoblottingSignal TransductionInterleukin-6Gene ExpressionT-Lymphocyte Subsets
Funding
- Memorial Sloan-Kettering Cancer Center
Citations
2,108
FWCI
59.09
field-weighted impact
References
50
Percentile
100%
vs. same field & year
Citations per year
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References
Control of Regulatory T Cell Development by the Transcription Factor <i>Foxp3</i>
Science · 2003 · 8,062 citations
IL-23 drives a pathogenic T cell population that induces autoimmune inflammation
The Journal of Experimental Medicine · 2005 · 4,029 citations
Stat6 Is Required for Mediating Responses to IL-4 and for the Development of Th2 Cells
Immunity · 1996 · 1,621 citations
TH-17 cells in the circle of immunity and autoimmunity
Nature Immunology · 2007 · 1,510 citations
TGFβ in the Context of an Inflammatory Cytokine Milieu Supports De Novo Differentiation of IL-17-Producing T Cells
Immunity · 2006 · 3,566 citations
Divergent Pro- and Antiinflammatory Roles for IL-23 and IL-12 in Joint Autoimmune Inflammation
The Journal of Experimental Medicine · 2003 · 1,633 citations
Increased expression of interleukin 17 in inflammatory bowel disease
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Interleukin (IL)-22 and IL-17 are coexpressed by Th17 cells and cooperatively enhance expression of antimicrobial peptides
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