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Increased expression of interleukin 17 in inflammatory bowel disease

Gut · 2002 · Vol. 52(1) · pp. 65–70
Sanae FujinoA AndohS BambaA OgawaK HataY ArakiT BambaY Fujiyama

Abstract

IL-17 expression in the mucosa and serum was increased in IBD patients. It is likely that IL-17 expression in IBD may be associated with altered immune and inflammatory responses in the intestinal mucosa.

Microscopic ColitisInflammatory Bowel DiseasePsoriasis: Treatment and PathogenesisUlcerative colitisInflammatory bowel diseaseMedicineColitisIntestinal mucosaProinflammatory cytokineImmunologyImmune systemInterleukinCD68

MeSH terms

Acute DiseaseColitisColitis, UlcerativeCrohn DiseaseHumansImmunohistochemistryIntestinal MucosaMacrophagesMonocytesRNA, MessengerT-LymphocytesInflammatory Bowel DiseasesCase-Control StudiesColitis, IschemicReverse Transcriptase Polymerase Chain Reaction

Funding

  • Ministry of Education, Culture, Sports, Science and Technology
Citations
1,688
FWCI
6.97
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53
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References
Human IL-17: a novel cytokine derived from T cells
The Journal of Immunology · 1995 · 1,020 citations
DNA sequencing with chain-terminating inhibitors
Proceedings of the National Academy of Sciences · 1977 · 69,196 citations
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