article Open AccessTop 1% cited
Stat6 Is Required for Mediating Responses to IL-4 and for the Development of Th2 Cells
Immunity · 1996 · Vol. 4(3) · pp. 313–319
Mark H. Kaplan(Harvard University)Ulrike SchindlerStephen T. Smiley(Harvard University)Michael J. Grusby✉(Harvard University)
Cytokine Signaling Pathways and InteractionsT-cell and B-cell ImmunologyImmune Response and InflammationSTAT6BiologyInterleukin 4Cell biologyImmunologyEmbryonic stem cellImmunoglobulin DSignal transductionTranscription factorMHC class II
MeSH terms
AnimalsCell DifferentiationImmunoglobulin ELymphocyte ActivationMembrane ProteinsMice, Mutant StrainsSignal TransductionTrans-ActivatorsInterleukin-4Up-RegulationT-Lymphocyte SubsetsTh2 CellsSTAT6 Transcription FactorMice
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References
IL-4 directs the development of Th2-like helper effectors.
The Journal of Immunology · 1990 · 1,257 citations
Accurate transcription initiation by RNA polymerase II in a soluble extract from isolated mammalian nuclei
Nucleic Acids Research · 1983 · 11,601 citations
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