review Open AccessTop 1% cited
The IL-23/Th17 Axis in the Immunopathogenesis of Psoriasis
Journal of Investigative Dermatology · 2009 · Vol. 129(6) · pp. 1339–1350
Antonella Di Cesare(King's College London)Paola Di Meglio(King's College London)Frank O. Nestlé✉(King's College London)
Psoriasis: Treatment and PathogenesisT-cell and B-cell ImmunologyImmunodeficiency and Autoimmune DisordersPsoriasisInterleukin 17Context (archaeology)ImmunologyPathogenesisInterleukin 23InflammationFunction (biology)MedicineT cell
MeSH terms
AnimalsClinical Trials as TopicT-Lymphocytes, Helper-InducerHumansImmune SystemModels, BiologicalPhosphorylationPsoriasisCytokinesProtein Structure, TertiaryReceptors, InterleukinCell ProliferationMiceInterleukin-23
Funding
- National Institute for Health and Care Research
- Research Councils UK
- Biomedical Research Council
Citations
1,092
FWCI
20.57
field-weighted impact
References
158
Percentile
100%
vs. same field & year
Citations per year
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References
A Receptor for the Heterodimeric Cytokine IL-23 Is Composed of IL-12Rβ1 and a Novel Cytokine Receptor Subunit, IL-23R
The Journal of Immunology · 2002 · 1,281 citations
Two types of murine helper T cell clone. I. Definition according to profiles of lymphokine activities and secreted proteins.
The Journal of Immunology · 1986 · 7,496 citations
IL-17 Plays an Important Role in the Development of Experimental Autoimmune Encephalomyelitis
The Journal of Immunology · 2006 · 1,525 citations
Possible Pathogenic Role of Th17 Cells for Atopic Dermatitis
Journal of Investigative Dermatology · 2008 · 665 citations
The differentiation of human TH-17 cells requires transforming growth factor-β and induction of the nuclear receptor RORγt
Nature Immunology · 2008 · 1,267 citations
A distinct lineage of CD4 T cells regulates tissue inflammation by producing interleukin 17
Nature Immunology · 2005 · 4,203 citations
Psoriasis Vulgaris Lesions Contain Discrete Populations of Th1 and Th17 T Cells
Journal of Investigative Dermatology · 2008 · 1,064 citations
IL‐22 regulates the expression of genes responsible for antimicrobial defense, cellular differentiation, and mobility in keratinocytes: a potential role in psoriasis
European Journal of Immunology · 2006 · 908 citations
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