reviewTop 10% cited
Pyruvate into lactate and back: From the Warburg effect to symbiotic energy fuel exchange in cancer cells
Radiotherapy and Oncology · 2009 · Vol. 92(3) · pp. 329–333
Olivier Féron✉(UCLouvain)
Cancer, Hypoxia, and MetabolismMitochondrial Function and PathologyATP Synthase and ATPases ResearchGlutaminolysisWarburg effectGlycolysisCitric acid cyclePentose phosphate pathwayBiochemistryAnaerobic glycolysisCancer cellOxidative phosphorylationChemistry
MeSH terms
Cell SurvivalEnergy MetabolismGlycolysisHumansNADNADPNeoplasmsOxidation-ReductionRadiation ToleranceSensitivity and SpecificityCell HypoxiaCell DeathPyruvic AcidLactic AcidCell Line, Tumor
Funding
- Fonds De La Recherche Scientifique - FNRS
Citations
553
FWCI
8.83
field-weighted impact
References
40
Percentile
98%
vs. same field & year
Citations per year
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References
Target of rapamycin (TOR): an integrator of nutrient and growth factor signals and coordinator of cell growth and cell cycle progression
Oncogene · 2004 · 1,243 citations
Targeting HIF-1 for cancer therapy
Nature reviews. Cancer · 2003 · 6,642 citations
HIF-1 mediates adaptation to hypoxia by actively downregulating mitochondrial oxygen consumption
Cell Metabolism · 2006 · 2,210 citations
HIF-1-mediated expression of pyruvate dehydrogenase kinase: A metabolic switch required for cellular adaptation to hypoxia
Cell Metabolism · 2006 · 3,827 citations
On the Origin of Cancer Cells
Science · 1956 · 13,149 citations
Why do cancers have high aerobic glycolysis?
Nature reviews. Cancer · 2004 · 4,733 citations
Attenuation of LDH-A expression uncovers a link between glycolysis, mitochondrial physiology, and tumor maintenance
Cancer Cell · 2006 · 1,584 citations
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