review Open AccessTop 1% cited
Coupling endoplasmic reticulum stress to the cell death program
Cell Death and Differentiation · 2004 · Vol. 11(4) · pp. 372–380
Rammohan V. Rao✉(Buck Institute for Research on Aging)H. Michael Ellerby(Buck Institute for Research on Aging)Dale E. Bredesen(University of California, San Francisco)
Endoplasmic Reticulum Stress and DiseaseAutophagy in Disease and TherapyRNA regulation and diseaseEndoplasmic reticulumUnfolded protein responseCell biologyProgrammed cell deathBiologyIntracellularApoptosisSignal transductionCytoplasmMitochondrion
MeSH terms
CalciumEndoplasmic ReticulumMitochondriaSignal TransductionApoptosisReceptors, Tumor Necrosis FactorCaspases
Funding
- U.S. Department of Defense
- Buck Institute for Research on Aging
- National Institutes of Health
Citations
1,197
FWCI
29.60
field-weighted impact
References
150
Percentile
100%
vs. same field & year
Citations per year
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References
Dynamic interaction of BiP and ER stress transducers in the unfolded-protein response
Nature Cell Biology · 2000 · 2,842 citations
Mammalian Caspases: Structure, Activation, Substrates, and Functions During Apoptosis
Annual Review of Biochemistry · 1999 · 2,764 citations
ER Stress Regulation of ATF6 Localization by Dissociation of BiP/GRP78 Binding and Unmasking of Golgi Localization Signals
Developmental Cell · 2002 · 1,429 citations
Life-or-death decisions by the Bcl-2 protein family
Trends in Biochemical Sciences · 2001 · 882 citations
The Endoplasmic Reticulum Stress-Responsive Protein GRP78 Protects Neurons Against Excitotoxicity and Apoptosis: Suppression of Oxidative Stress and Stabilization of Calcium Homeostasis
Experimental Neurology · 1999 · 439 citations
Gadd153 Sensitizes Cells to Endoplasmic Reticulum Stress by Down-Regulating Bcl2 and Perturbing the Cellular Redox State
Molecular and Cellular Biology · 2001 · 1,882 citations
Translational Control Is Required for the Unfolded Protein Response and In Vivo Glucose Homeostasis
Molecular Cell · 2001 · 1,342 citations
CHOP is implicated in programmed cell death in response to impaired function of the endoplasmic reticulum
Genes & Development · 1998 · 2,003 citations
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