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Cell death and endoplasmic reticulum stress: disease relevance and therapeutic opportunities

Nature Reviews Drug Discovery · 2008 · Vol. 7(12) · pp. 1013–1030
Inki KimWenjie XuJohn C. Reed
Endoplasmic Reticulum Stress and DiseaseAutophagy in Disease and TherapyPancreatic function and diabetesUnfolded protein responseEndoplasmic reticulumProgrammed cell deathCell biologyNeurodegenerationSignal transductionBiologyEndoplasmic-reticulum-associated protein degradationApoptosisImmunology

MeSH terms

AnimalsAntineoplastic AgentsEndoplasmic ReticulumHumansNeoplasmsProtein DenaturationStress, PhysiologicalDrug DesignSignal TransductionReperfusion InjuryCell DeathApoptosisProtein FoldingOxidative StressMolecular Chaperones
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