articleTop 10% cited
The Endoplasmic Reticulum Stress-Responsive Protein GRP78 Protects Neurons Against Excitotoxicity and Apoptosis: Suppression of Oxidative Stress and Stabilization of Calcium Homeostasis
Experimental Neurology · 1999 · Vol. 155(2) · pp. 302–314
ZaiFang Yu✉(University of Kentucky)Hong Luo(University of Kentucky)Weiming Fu(University of Kentucky)Mark P. Mattson(University of Kentucky)
Endoplasmic Reticulum Stress and DiseaseNerve injury and regenerationAlzheimer's disease research and treatmentsEndoplasmic reticulumUnfolded protein responseOxidative stressExcitotoxicityNeuroprotectionCell biologyCalcium in biologyProgrammed cell deathApoptosisCalcium
MeSH terms
Endoplasmic Reticulum Chaperone BiPAnimalsCalciumCarrier ProteinsEndoplasmic ReticulumFerric CompoundsHeat-Shock ProteinsHippocampusHomeostasisImmunohistochemistryMitochondriaNeuronsBlotting, WesternPC12 CellsApoptosis
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Calcium and reactive oxygen species mediate staurosporine-induced mitochondrial dysfunction and apoptosis in PC12 cells
Journal of Neuroscience Research · 1998 · 380 citations
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Experimental Neurology · 1994 · 444 citations
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Activation of NF-?B protects hippocampal neurons against oxidative stress-induced apoptosis: Evidence for induction of manganese superoxide dismutase and suppression of peroxynitrite production and protein tyrosine nitration
Journal of Neuroscience Research · 1997 · 567 citations
beta-Amyloid peptides destabilize calcium homeostasis and render human cortical neurons vulnerable to excitotoxicity
Journal of Neuroscience · 1992 · 1,614 citations
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