article Open AccessTop 1% cited
Caspase-1-induced pyroptosis is an innate immune effector mechanism against intracellular bacteria
Nature Immunology · 2010 · Vol. 11(12) · pp. 1136–1142
Edward A. Miao✉(Seattle University)Irina A. Leaf(Institute for Systems Biology)Piper M. Treuting(University of Washington)Dat P. Mao(Institute for Systems Biology)Monica Dors(Institute for Systems Biology)Anasuya Sarkar(Sacred Heart Hospital)Sarah Warren(Seattle University)Mark D. Wewers(Sacred Heart Hospital)Alan Aderem(Seattle University)
Inflammasome and immune disordersinterferon and immune responsesImmune Response and InflammationPyroptosisInflammasomeInnate immune systemFlagellinMicrobiologyBiologyLegionella pneumophilaNLRC4EffectorCaspase 1
MeSH terms
AnimalsCalcium-Binding ProteinsCell SeparationEnzyme-Linked Immunosorbent AssayFlow CytometryImmunity, InnateImmunohistochemistryMacrophagesMice, Inbred C57BLSalmonella InfectionsSalmonella typhimuriumApoptosisCaspase 1Apoptosis Regulatory ProteinsMice
Citations
1,324
FWCI
30.56
field-weighted impact
References
53
Percentile
100%
vs. same field & year
Citations per year
Cited by
Regulation of inflammasome activation
Immunological Reviews · 2015 · 1,061 citations
Pyroptotic cell death defends against intracellular pathogens
Immunological Reviews · 2015 · 1,027 citations
Pattern Recognition Receptors and the Host Cell Death Molecular Machinery
Frontiers in Immunology · 2018 · 719 citations
Molecular mechanisms and functions of pyroptosis, inflammatory caspases and inflammasomes in infectious diseases
Immunological Reviews · 2017 · 1,646 citations
The NLRP3 Inflammasome: An Overview of Mechanisms of Activation and Regulation
International Journal of Molecular Sciences · 2019 · 3,306 citations
<scp>GSDMD</scp> membrane pore formation constitutes the mechanism of pyroptotic cell death
The EMBO Journal · 2016 · 1,131 citations
Nicotine promotes atherosclerosis via ROS-NLRP3-mediated endothelial cell pyroptosis
Cell Death and Disease · 2018 · 595 citations
Pyroptosis: Gasdermin-Mediated Programmed Necrotic Cell Death
Trends in Biochemical Sciences · 2016 · 3,053 citations
References
Pyroptosis: host cell death and inflammation
Nature Reviews Microbiology · 2009 · 3,189 citations
Differential Regulation of Caspase-1 Activation, Pyroptosis, and Autophagy via Ipaf and ASC in Shigella-Infected Macrophages
PLoS Pathogens · 2007 · 530 citations
Construction of versatile low-copy-number vectors for cloning, sequencing and gene expression in Escherichia coli
Gene · 1991 · 1,178 citations
The AIM2 inflammasome is essential for host defense against cytosolic bacteria and DNA viruses
Nature Immunology · 2010 · 1,284 citations
Immunological and Inflammatory Functions of the Interleukin-1 Family
Annual Review of Immunology · 2009 · 3,402 citations
Citation Network
How this paper connects to the literature. Drag to explore, click any node to open that paper.