review Open AccessTop 1% cited
Inflammatory caspases and inflammasomes: master switches of inflammation
Cell Death and Differentiation · 2006 · Vol. 14(1) · pp. 10–22
Fabio Martinon✉(University of Lausanne)Jürg Tschopp(University of Lausanne)
Inflammasome and immune disordersFatty Acid Research and HealthCholesterol and Lipid MetabolismCaspaseProteasesBiologyCell biologyNLRP1Caspase 1Innate immune systemInflammationInflammasomeApoptosis
MeSH terms
Amino Acid SequenceAnimalsEndoplasmic ReticulumEnzyme ActivationHumansImmunity, InnateInflammationMolecular Sequence DataReproductionSepsisCaspasesMultiprotein ComplexesAdaptor Proteins, Signal TransducingApoptosis Regulatory ProteinsInterleukin-1beta
Funding
- National Science Foundation
- Schweizerischer Nationalfonds zur Förderung der Wissenschaftlichen Forschung
Citations
819
FWCI
22.53
field-weighted impact
References
139
Percentile
100%
vs. same field & year
Citations per year
Cited by
Chondrocyte Apoptosis in the Pathogenesis of Osteoarthritis
International Journal of Molecular Sciences · 2015 · 903 citations
Immunological and Inflammatory Functions of the Interleukin-1 Family
Annual Review of Immunology · 2009 · 3,402 citations
The Inflammasomes: Guardians of the Body
Annual Review of Immunology · 2009 · 2,393 citations
Caspases in apoptosis and beyond
Oncogene · 2008 · 1,070 citations
Redox control of cell fate by MAP kinase: physiological roles of ASK1-MAP kinase pathway in stress signaling
Biochimica et Biophysica Acta (BBA) - General Subjects · 2008 · 493 citations
Activation of the NALP3 inflammasome is triggered by low intracellular potassium concentration
Cell Death and Differentiation · 2007 · 1,418 citations
Macrophage activation by endogenous danger signals
The Journal of Pathology · 2007 · 608 citations
The inflammasome: a caspase-1-activation platform that regulates immune responses and disease pathogenesis
Nature Immunology · 2009 · 1,825 citations
References
The Inflammasome
Molecular Cell · 2002 · 5,936 citations
The role of inflammation in CNS injury and disease
British Journal of Pharmacology · 2006 · 1,263 citations
The CD95(APO-1/Fas) DISC and beyond
Cell Death and Differentiation · 2003 · 1,064 citations
Flagellin-Deficient Legionella Mutants Evade Caspase-1- and Naip5-Mediated Macrophage Immunity
PLoS Pathogens · 2006 · 535 citations
The tripartite motif family identifies cell compartments
The EMBO Journal · 2001 · 1,363 citations
NALP3 Forms an IL-1β-Processing Inflammasome with Increased Activity in Muckle-Wells Autoinflammatory Disorder
Immunity · 2004 · 1,736 citations
Citation Network
How this paper connects to the literature. Drag to explore, click any node to open that paper.