review Open AccessTop 1% cited
Greasing the Wheels of the Cancer Machine: The Role of Lipid Metabolism in Cancer
Cell Metabolism · 2019 · Vol. 31(1) · pp. 62–76
Marteinn T. Snaebjornsson✉(German Cancer Research Center)Sudha Janaki‐Raman✉Almut Schulze✉(Heidelberg University)
Cancer, Lipids, and MetabolismCancer, Hypoxia, and MetabolismLipid metabolism and biosynthesisLipid metabolismLipidomeCancer cellCancerBiologyCell metabolismBiochemistryFunction (biology)Cell signalingMetabolism
MeSH terms
FerroptosisCholesterolEnergy MetabolismFatty AcidsHumansNeoplasmsStress, PhysiologicalNeoplastic Stem CellsSignal TransductionLipid MetabolismTumor Microenvironment
Funding
- Deutsche Forschungsgemeinschaft
Citations
1,058
FWCI
24.83
field-weighted impact
References
166
Percentile
100%
vs. same field & year
Citations per year
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References
Acetyl Coenzyme A: A Central Metabolite and Second Messenger
Cell Metabolism · 2015 · 1,310 citations
Activation of a Metabolic Gene Regulatory Network Downstream of mTOR Complex 1
Molecular Cell · 2010 · 1,954 citations
Fatty acid-binding proteins: role in metabolic diseases and potential as drug targets
Nature Reviews Drug Discovery · 2008 · 1,751 citations
Regulation of Ferroptotic Cancer Cell Death by GPX4
Cell · 2014 · 7,213 citations
Inactivation of the ferroptosis regulator Gpx4 triggers acute renal failure in mice
Nature Cell Biology · 2014 · 3,521 citations
Adipocytes promote ovarian cancer metastasis and provide energy for rapid tumor growth
Nature Medicine · 2011 · 2,230 citations
Inhibition of fatty acid oxidation by etomoxir impairs NADPH production and increases reactive oxygen species resulting in ATP depletion and cell death in human glioblastoma cells
Biochimica et Biophysica Acta (BBA) - Bioenergetics · 2010 · 460 citations
SREBP Activity Is Regulated by mTORC1 and Contributes to Akt-Dependent Cell Growth
Cell Metabolism · 2008 · 1,365 citations
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