review Open AccessTop 1% cited
Machine learning for the prediction of sepsis: a systematic review and meta-analysis of diagnostic test accuracy
Intensive Care Medicine · 2020 · Vol. 46(3) · pp. 383–400
Lucas M. Fleuren✉(Amsterdam Neuroscience)Thomas Klausch(Vrije Universiteit Amsterdam)Charlotte Zwager(Amsterdam University Medical Centers)Linda Schoonmade(Amsterdam University Medical Centers)Tingjie Guo(Amsterdam University Medical Centers)Luca F. Roggeveen(Amsterdam University Medical Centers)Eleonora L. Swart(Amsterdam University Medical Centers)Armand R. J. Girbes(Amsterdam University Medical Centers)Patrick Thoral(Amsterdam University Medical Centers)Ari Ercole(University of Cambridge)Mark Hoogendoorn(Vrije Universiteit Amsterdam)Paul Elbers(European Society of Intensive Care Medicine)
Abstract
This systematic review and meta-analysis show that on retrospective data, individual machine learning models can accurately predict sepsis onset ahead of time. Although they present alternatives to traditional scoring systems, between-study heterogeneity limits the assessment of pooled results. Systematic reporting and clinical implementation studies are needed to bridge the gap between bytes and bedside.
Sepsis Diagnosis and TreatmentClinical Reasoning and Diagnostic SkillsMachine Learning in HealthcareMedicineReceiver operating characteristicSepsisChecklistMeta-analysisMEDLINESeptic shockEmergency medicineIntensive care unitIntensive care
MeSH terms
Machine LearningDiagnostic Tests, RoutineHumansRetrospective StudiesShock, SepticSepsis
Citations
694
FWCI
52.51
field-weighted impact
References
68
Percentile
100%
vs. same field & year
Citations per year
References
Duration of hypotension before initiation of effective antimicrobial therapy is the critical determinant of survival in human septic shock*
Critical Care Medicine · 2006 · 6,021 citations
Empiric Antibiotic Treatment Reduces Mortality in Severe Sepsis and Septic Shock From the First Hour
Critical Care Medicine · 2014 · 1,445 citations
QUADAS-2: A Revised Tool for the Quality Assessment of Diagnostic Accuracy Studies
Annals of Internal Medicine · 2011 · 13,616 citations
Assessment of Global Incidence and Mortality of Hospital-treated Sepsis: Current Estimates and Limitations
American Journal of Respiratory and Critical Care Medicine · 2015 · 3,532 citations
The Third International Consensus Definitions for Sepsis and Septic Shock (Sepsis-3)
JAMA · 2016 · 27,000 citations
Assessment of Clinical Criteria for Sepsis
JAMA · 2016 · 3,698 citations
Surviving Sepsis Campaign: International Guidelines for Management of Sepsis and Septic Shock: 2016
Intensive Care Medicine · 2017 · 6,685 citations
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