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Rapid and precise alignment of raw reads against redundant databases with KMA

BMC Bioinformatics · 2018 · Vol. 19(1) · pp. 307–307
Philip T. L. C. ClausenFrank M. AarestrupOle Lund

Abstract

With KMA, it was possible map raw reads directly against redundant databases with high accuracy, speed and memory efficiency.

Genomics and Phylogenetic StudiesMycobacterium research and diagnosisBacteriophages and microbial interactionsDatabaseComputer scienceMultilocus sequence typingGenomeSortingData miningDNA sequencingRaw dataComputational biologyBiology

MeSH terms

AlgorithmsComputer SimulationHumansSoftwareGenome, HumanDatabases, FactualSequence AlignmentSequence Analysis, DNAComputational BiologyHigh-Throughput Nucleotide Sequencing

Funding

  • European Commission
  • Center for Genomic Epidemiology
Citations
894
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15.96
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References
16
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100%
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References
The Sequence Alignment/Map format and SAMtools
Bioinformatics · 2009 · 66,208 citations
Identification of acquired antimicrobial resistance genes
Journal of Antimicrobial Chemotherapy · 2012 · 5,069 citations
Fast gapped-read alignment with Bowtie 2
Nature Methods · 2012 · 59,710 citations
Minimap2: pairwise alignment for nucleotide sequences
Bioinformatics · 2018 · 16,068 citations
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