article Open AccessTop 1% cited
ResFinder 4.0 for predictions of phenotypes from genotypes
Journal of Antimicrobial Chemotherapy · 2020 · Vol. 75(12) · pp. 3491–3500
Valeria Bortolaia(Technical University of Denmark)Rolf Sommer Kaas(Technical University of Denmark)Étienne Ruppé(Inserm)Marilyn C. Roberts(University of Washington)Štefan Schwarz(Freie Universität Berlin)Vincent Cattoir(Inserm)A. Philippon(Délégation Paris 5)Rosa Lundbye Allesøe(University of Copenhagen)Ana Rita Rebelo(Technical University of Denmark)Alfred Ferrer Florensa(Technical University of Denmark)Linda Fagelhauer(Justus-Liebig-Universität Gießen)Trinad Chakraborty(Justus-Liebig-Universität Gießen)Bernd Neumann(Robert Koch Institute)Guido Werner(Robert Koch Institute)Jennifer K. Bender(Robert Koch Institute)Kerstin Stingl(Federal Institute for Risk Assessment)Minh Ngoc Nguyen(University of Antwerp)Jasmine Coppens(University of Antwerp)Basil Britto Xavier(University of Antwerp)Surbhi Malhotra‐Kumar(University of Antwerp)Henrik Westh(University of Copenhagen)Mette Pinholt(Hvidovre Hospital)Muna F. Anjum(Animal and Plant Health Agency)Nicholas Duggett(Animal and Plant Health Agency)Isabelle Kempf(Agence Nationale de Sécurité Sanitaire de l’Alimentation, de l’Environnement et du Travail)Suvi Nykäsenoja(Finnish Food Authority)Satu Olkkola(Finnish Food Authority)Kinga Wieczorek(National Veterinary Research Institute)Ana Amaro(Instituto Nacional de Investigação Agrária e Veterinária)Lurdes Clemente(Instituto Nacional de Investigação Agrária e Veterinária)Joël Mossong(Laboratoire National de Santé)Serge Losch(Laboratoire National de Santé)Catherine Ragimbeau(Laboratoire National de Santé)Ole Lund(Technical University of Denmark)Frank M. Aarestrup✉(Technical University of Denmark)
Abstract
WGS-based AST using ResFinder 4.0 provides in silico antibiograms as reliable as those obtained by phenotypic AST at least for the bacterial species/antimicrobial agents of major public health relevance considered.
Genomics and Phylogenetic StudiesMolecular Biology Techniques and ApplicationsMetabolomics and Mass Spectrometry StudiesGenotypePhenotypeBiologyGeneticsComputational biologyGene
MeSH terms
AnimalsAnti-Bacterial AgentsGenotypeHumansMicrobial Sensitivity TestsPhenotypeDrug Resistance, Bacterial
Funding
- Deutsches Zentrum für Infektionsforschung
- Koch Institute for Integrative Cancer Research, Massachusetts Institute of Technology
- European Commission
- Bundesministerium für Bildung und Forschung
- Novo Nordisk
- Novo Nordisk Fonden
- Państwowy Instytut Weterynaryjny - Państwowy Instytut Badawczy
- Robert Koch Institut
Citations
3,091
FWCI
125.65
field-weighted impact
References
47
Percentile
100%
vs. same field & year
Citations per year
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References
Identification of acquired antimicrobial resistance genes
Journal of Antimicrobial Chemotherapy · 2012 · 5,069 citations
The worldwide emergence of plasmid-mediated quinolone resistance
The Lancet Infectious Diseases · 2006 · 964 citations
PointFinder: a novel web tool for WGS-based detection of antimicrobial resistance associated with chromosomal point mutations in bacterial pathogens
Journal of Antimicrobial Chemotherapy · 2017 · 779 citations
Rapid and precise alignment of raw reads against redundant databases with KMA
BMC Bioinformatics · 2018 · 894 citations
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