reviewTop 1% cited

Mechanism and medical implications of mammalian autophagy

Nature Reviews Molecular Cell Biology · 2018 · Vol. 19(6) · pp. 349–364

Ivan Đikić✉(Goethe University Frankfurt)Zvulun Elazar✉(Weizmann Institute of Science)

Autophagy in Disease and Therapy Cannabis and Cannabinoid ResearchAutophagyNeurodegenerationCell biologyContext (archaeology)BiologyMechanism (biology)Programmed cell deathNeuroscienceApoptosisMedicine

MeSH terms

AnimalsAutophagyHumansMammalsNeoplasmsNeurodegenerative Diseases

Citations

2,711

FWCI

174.21

field-weighted impact

References

202

Percentile

100%

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Citations per year

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References

Tissue fractionation studies. 6. Intracellular distribution patterns of enzymes in rat-liver tissue

Biochemical Journal · 1955 · 4,150 citations

AMPK and mTOR regulate autophagy through direct phosphorylation of Ulk1

Nature Cell Biology · 2011 · 6,906 citations

Autophagy: Renovation of Cells and Tissues

Cell · 2011 · 6,245 citations

Isolation and characterization of autophagy‐defective mutants of <i>Saccharomyces cerevisiae</i>

FEBS Letters · 1993 · 1,727 citations

p62/SQSTM1 Binds Directly to Atg8/LC3 to Facilitate Degradation of Ubiquitinated Protein Aggregates by Autophagy

Journal of Biological Chemistry · 2007 · 4,501 citations

FoxO3 Controls Autophagy in Skeletal Muscle In Vivo

Cell Metabolism · 2007 · 1,898 citations

Cargo recognition and trafficking in selective autophagy

Nature Cell Biology · 2014 · 1,199 citations

Pancreatic cancers require autophagy for tumor growth

Genes & Development · 2011 · 1,450 citations

Autophagy-dependent cell death

Cell Death and Differentiation · 2018 · 746 citations

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