article Open AccessTop 1% cited
Batch effects in single-cell RNA-sequencing data are corrected by matching mutual nearest neighbors
Nature Biotechnology · 2018 · Vol. 36(5) · pp. 421–427
Laleh Haghverdi✉(European Bioinformatics Institute)Aaron T. L. Lun(University of Cambridge)Michael D. Morgan(Wellcome Sanger Institute)John C. Marioni(European Bioinformatics Institute)
Single-cell and spatial transcriptomicsExtracellular vesicles in diseaseCancer Genomics and DiagnosticsMatching (statistics)PopulationComputer scienceSingle cell sequencingRNAData miningRNA-SeqComputational biologyk-nearest neighbors algorithmArtificial intelligence
MeSH terms
Data AnalysisAlgorithmsCluster AnalysisSequence Analysis, RNASingle-Cell AnalysisHigh-Throughput Nucleotide Sequencing
Citations
2,662
FWCI
96.05
field-weighted impact
References
32
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100%
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References
Smart-seq2 for sensitive full-length transcriptome profiling in single cells
Nature Methods · 2013 · 2,549 citations
Normalization of RNA-seq data using factor analysis of control genes or samples
Nature Biotechnology · 2014 · 2,258 citations
Highly Parallel Genome-wide Expression Profiling of Individual Cells Using Nanoliter Droplets
Cell · 2015 · 7,706 citations
featureCounts: an efficient general purpose program for assigning sequence reads to genomic features
Bioinformatics · 2013 · 28,111 citations
limma powers differential expression analyses for RNA-sequencing and microarray studies
Nucleic Acids Research · 2015 · 41,828 citations
STAR: ultrafast universal RNA-seq aligner
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