article Open AccessTop 1% cited

NLRP3 inflammasome blockade reduces liver inflammation and fibrosis in experimental NASH in mice

Journal of Hepatology · 2017 · Vol. 66(5) · pp. 1037–1046

Auvro R. Mridha(Australian National University)Alexander Wree(University of California, San Diego)Avril A. B. Robertson(University of Queensland)Matthew M. Yeh(University of Washington)Casey D. Johnson(University of California, San Diego)Derrick M. Van Rooyen(Canberra Hospital)Fahrettin Haczeyni(Canberra Hospital)Narci Teoh(Australian National University)Christopher Savard(University of Washington)George N. Ioannou(University of Washington)Seth L. Masters(Walter and Eliza Hall Institute of Medical Research)Kate Schroder(University of Queensland)Matthew A. Cooper(University of Queensland)Ariel E. Feldstein(University of California, San Diego)Geoffrey C. Farrell✉(Canberra Hospital)

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Liver Disease Diagnosis and Treatment Inflammasome and immune disorders Liver Disease and TransplantationInflammasomeSteatohepatitisFibrosisInflammationFatty liverLiver injuryMedicineEndocrinologyCholesterolInternal medicine

MeSH terms

NLR Family, Pyrin Domain-Containing 3 ProteinAnimalsDisease Models, AnimalFemaleFuransHepatitisHeterocyclic Compounds, 4 or More RingsIndenesLiver Cirrhosis, ExperimentalSulfonamidesSulfonesNF-kappa BReactive Oxygen SpeciesMiceInterleukin-1beta

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1,037

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46.08

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100%

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Cited by

Liver Fibrosis: Mechanistic Concepts and Therapeutic Perspectives